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美國Primary Monkey Podocyte 猴原代腎足細胞
美國(guo)PrimCells原代(dai)(dai)細(xi)(xi)胞(bao):PrimCells的原代(dai)(dai)細(xi)(xi)胞(bao)產(chan)(chan)品采用*的高(gao)效(xiao)提取方法, 分離(li),并通過(guo)盡(jin)量縮短體外培養時間從而保(bao)證其(qi)更接近體原始狀態,以適應(ying)客戶對細(xi)(xi)胞(bao)品質的嚴(yan)格要求。PrimCells亦是多(duo)(duo)種腎(shen)臟來源原代(dai)(dai)細(xi)(xi)胞(bao)的世界(jie)獨jia供(gong)應(ying)商,為多(duo)(duo)家藥(yao)(yao)物(wu)研發企業提供(gong)藥(yao)(yao)物(wu)藥(yao)(yao)效(xiao)與毒理測(ce)試。此外,PrimCells還(huan)開發出多(duo)(duo)種轉基因胚(pei)胎干細(xi)(xi)胞(bao)、原代(dai)(dai)胚(pei)胎成纖維(wei)細(xi)(xi)胞(bao)等產(chan)(chan)品,是干細(xi)(xi)胞(bao)與重編程領(ling)域的報告基因原代(dai)(dai)細(xi)(xi)胞(bao)提供(gong)商。
Species: | Macaque Monkey | Catalog Number: | PCKDP01 |
Cell Number: | ~1x106 | Storage/Shipping: | Dry Ice |
Introduction:
Podocytes are a group of terminally differentiated cells located in the outer aspect of glomerular basement membrane (GBM). They have special morphology with multiple long foot processes that cover the entire outer surface of the capillary of glomerulus and form a tight barrier to filter the blood and form the initial urine1. These cells are very important to maintain the normal function of the kidney and podocyte injury could result in massive proteinuria and eventually kidney failure2, 3.
PrimCells is proud to isolate and provide the primary cultures of podocytes from non-human primates (Macaca Fascicularis, also known as Cynomolgus Macaques) to the research community. These cells have been isolated using traditional sieving method and are confirmed to express typical podocyte markers such as Nephrin, Synaptopodin and WT1 and can be a valuable tool to study the function of genes in nephrology and/or drug induced toxicity in glomerular injury.
美國Primary Monkey Podocyte 猴原代腎足細胞
美國PrimCells品(pin)牌介(jie)紹(shao)
PrimCells是位于(yu)美國加州(zhou)圣(sheng)迭(die)戈的(de)一(yi)家專業致力于(yu)細(xi)胞(bao)產品研發和解決方案提供的(de)業內技術。
公司(si)(si)匯集了(le)資深的(de)(de)(de)生物醫藥技術專(zhuan)家(jia),獨立(li)開(kai)發了(le)多項原代細胞(bao)和干細胞(bao)相關(guan)的(de)(de)(de)專(zhuan)有技術。 公司(si)(si)以“細胞(bao)研(yan)究的(de)(de)(de)優選擇"為宗旨,自主研(yan)發超過70種創新產(chan)品(pin),多個(ge)特種細胞(bao)市場的(de)(de)(de)空白(bai)。例如其誘導(dao)性表達細胞(bao)庫(ku)和高效3D皮膚培養系統,皆為該類(lei)產(chan)品(pin)目前市場上少數(shu)的(de)(de)(de)規(gui)模化(hua)供應商。此外,公司(si)(si)以高質量的(de)(de)(de)數(shu)據與快速穩定的(de)(de)(de)項目完成時間,長(chang)期(qi)為多家(jia)制藥公司(si)(si)提(ti)供解決方案,獲得用戶廣(guang)泛(fan)贊譽。
PrimCells產品線:
報告基因干細胞 2. 原代細胞(含報告基因原代細胞) 3. 誘導性穩定細胞株
4. 人源重(zhong)組蛋白 5. 創(chuang)新型培養試(shi)劑
PrimCells 解(jie)決方案
1.誘導性(xing)穩定細胞株(zhu)開發 2. 原(yuan)代細胞開發 3. 藥物(wu)體(ti)外毒理和效能測試 4. 3D-皮(pi)膚培養(yang)
PrimCells合作伙伴(ban)及客戶:
A.生物制藥(yao)公司:輝瑞(Pfizer), 諾(nuo)華(Novartis), 禮來(lai)(Eli2 Lilly),. Amgen, EMD Millipore, Regeneron等公司的毒理(li)和醫藥(yao)研發部門
B.科(ke)研機構:冷泉港實驗(yan)室,哈佛醫學院, 麻省理工(MIT),, UCSF, NYU, Salk, UIUC, USC等
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