簡要(yao)描述(shu):美國人RXR alpha可誘導表達穩定細胞株美(mei)國PrimCells誘(you)(you)(you)導性穩(wen)定細(xi)(xi)胞株: PrimCells建立的(de)(de)(de)*的(de)(de)(de)誘(you)(you)(you)導性細(xi)(xi)胞高(gao)效(xiao)開發系統,能在(zai)極短時間內(nei)篩(shai)(shai)選出低泄漏,高(gao)誘(you)(you)(you)導性的(de)(de)(de)穩(wen)定細(xi)(xi)胞株,成(cheng)功開發出一系列核受體誘(you)(you)(you)導表達的(de)(de)(de)穩(wen)定細(xi)(xi)胞株產(chan)品,為多家(jia)制(zhi)藥公司研發部門和(he)科研院(yuan)所提供產(chan)品與服(fu)務(wu),廣受用戶好評。針對客戶的(de)(de)(de)特定需求,PrimCells亦提供量(liang)身定制(zhi)服(fu)務(wu),通過密(mi)切(qie)的(de)(de)(de)客戶交流和(he)高(gao)效(xiao)的(de)(de)(de)篩(shai)(shai)選體系
產品分類
Product Category相關文章
Related Articles詳細介紹
美國人RXR alpha可誘導表達穩定細胞株
美國PrimCells誘(you)(you)導(dao)性穩(wen)(wen)定細胞株: PrimCells建立的(de)(de)*的(de)(de)誘(you)(you)導(dao)性細胞高效(xiao)開發系統,能在極短時間(jian)內(nei)篩選(xuan)出(chu)低泄(xie)漏,高誘(you)(you)導(dao)性的(de)(de)穩(wen)(wen)定細胞株,成功開發出(chu)一系列核(he)受體誘(you)(you)導(dao)表達的(de)(de)穩(wen)(wen)定細胞株產品,為多家(jia)制藥公司研發部門和(he)科(ke)研院所提(ti)供產品與服務,廣(guang)受用戶(hu)好評。針對客(ke)(ke)戶(hu)的(de)(de)特(te)定需求,PrimCells亦提(ti)供量(liang)身定制服務,通過密(mi)切的(de)(de)客(ke)(ke)戶(hu)交(jiao)流和(he)高效(xiao)的(de)(de)篩選(xuan)體系,嚴格保(bao)證(zheng)客(ke)(ke)戶(hu)在3-4周內(nei)即獲得高質量(liang)的(de)(de)誘(you)(you)導(dao)性穩(wen)(wen)定細胞株,具有市(shi)場其(qi)他供應(ying)商*的(de)(de)時效(xiao)性。
美國人RXR alpha可誘導表達穩定細胞株
Nuclear hormone receptors (NHRs) are a superfamily of transcription factors that function as powerful metabolic regulators to control a variety of systemic processes in physiology. They also play key roles in the pathophysiology of many major disease states, such as diabetes, obesity, inflammation, atherosclerosis and heart failure. To date, this superfamily has provided a rich source of drug design targets and it is continuing to be one of the hottest areas for pharmaceutical researches.
PrimCells now provides a comprehensive set of NHR expressing cell lines to the research community. These high-quality, flag-and/or HA-tagged NHR-expressing cell lines aim to facilitate further biochemical and molecular studies of their functions and hence encourage new strategies for drug design.
The human VDR stable cell line was created by stable co-transfection of HEK293 cells with two plasmids expressing the bacterial Tet repressor (TetR) and the human VDR protein with HA tag, respectively. Since the human VDR gene is driven by a promoter containing two tetracycline operator (TeTO2) sites, its expression can be induced by doxycycline.
美國PrimCells品牌(pai)介紹(shao)
PrimCells是位于美國(guo)加州圣(sheng)迭(die)戈的一(yi)家專業致力于細胞產品研(yan)發和解決(jue)方案提供的業內技術(shu)。
公(gong)司匯集了資深的(de)(de)生(sheng)物醫(yi)藥技術專家,獨立(li)開發了多項原(yuan)代細胞和(he)干細胞相(xiang)關的(de)(de)專有技術。 公(gong)司以“細胞研(yan)究(jiu)的(de)(de)優選(xuan)擇"為宗旨,自(zi)主研(yan)發超(chao)過70種(zhong)創(chuang)新(xin)產(chan)(chan)品(pin),多個特種(zhong)細胞市(shi)場的(de)(de)空白。例如其誘導性表達(da)細胞庫(ku)和(he)高效3D皮(pi)膚培養系統,皆為該(gai)類產(chan)(chan)品(pin)目(mu)前(qian)市(shi)場上少(shao)數(shu)的(de)(de)規模化供應商。此外,公(gong)司以高質量的(de)(de)數(shu)據與快速(su)穩定的(de)(de)項目(mu)完成時間,長期為多家制藥公(gong)司提(ti)供解決(jue)方案,獲得用戶廣(guang)泛贊譽(yu)。
PrimCells產品(pin)線:
報告基因干細(xi)(xi)(xi)胞(bao) 2. 原(yuan)代(dai)細(xi)(xi)(xi)胞(bao)(含報告基因原(yuan)代(dai)細(xi)(xi)(xi)胞(bao)) 3. 誘導(dao)性穩定細(xi)(xi)(xi)胞(bao)株
4. 人源(yuan)重組蛋白 5. 創新(xin)型培養(yang)試(shi)劑
PrimCells 解決方案
1.誘導性穩定細胞(bao)(bao)株(zhu)開發 2. 原代(dai)細胞(bao)(bao)開發 3. 藥物體外毒(du)理和效能(neng)測(ce)試(shi) 4. 3D-皮膚培(pei)養
PrimCells合作伙(huo)伴及客戶:
A.生物制藥公(gong)司:輝(hui)瑞(Pfizer), 諾華(Novartis), 禮來(Eli2 Lilly),. Amgen, EMD Millipore, Regeneron等公(gong)司的毒理(li)和醫藥研發(fa)部門(men)
B.科研機構(gou):冷泉港(gang)實驗室,哈佛醫(yi)學(xue)院(yuan), 麻(ma)省理工(MIT),, UCSF, NYU, Salk, UIUC, USC等(deng)
產品咨詢
掃一掃 微信咨詢